1、 公司概况
北京瑞恒比邻教育科技有限公司成立于2010年12月,注册资本为110万元,为一家提供互联网教育产品和服务的教育科技公司。
公司的核心品牌为“学通数学”,核心业务是:提供面向中小学生的数学、奥数的视频、直播课程产品和服务。目前,公司已累积有超过3年的视频课程制作经验,以及1年半的在线互动直播服务经验,并和多个在线教育平台、渠道展开了合作。
公司的全职员工共10人,其中,2人毕业于清华大学,3人有7年或以上的教育培训行业经验,9人在比邻公司工作超过2年,7人为数学教师。
2、 公司文化
学通数学的核心使命为:提供学生认可的在线学习服务。
3、 公司主要产品
视频课程:小学数学同步课,奥数专题课、同步课,初中数学同步课、备考专题课等;
直播课程:小学数学、奥数、初中数学的同步课、公开课、答疑课等。
4、 重要合作伙伴
学通数学已经积极和多个开放平台、渠道展开了合作,以期双赢。
目前,主要的合作伙伴包括:全通教育、新东方在线、义方教育、传课、淘宝同学、网易云课堂、好课网、233网校等。
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文章来源: 学通
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Recent studies have reported conflicting results about the sensitivity of serum cysC compared to creatinine in predicting various forms of AKI. This phenomenon does not always indicate a psychiatric disorder and can be seen in persons without mental disorders. mirtazapine.olanzapine.doxylamine The risk of RCC development is associated with increased duration and severity of elevated blood pressure. Glucose also is the major myocardial fuel during ischemia, since ischemia impairs mitochondrial fatty acid oxidation. lexapro.digitek.fast Patients with typical clusters of symptoms, such as those associated with anticholinesterase agents, may provide clues to the type of chemical and guide treatment. One trial was conducted in Europe and showed greater time in the therapeutic INR range with genotype-guided dosing compared to a standard dosing approach. Healthcare professionals are obligated to ensure that medications are used safely and errors are prevented. dapsone.glumet.nasacort Functional MRI visualizes blood flow to focal areas of the brain by measurement differences in oxygenated blood concentrations to determine areas of greater activity. Permethrin and pyrethrins plus piperonyl butoxide should be used with nit combs because these agents are pediculocidal, but nonovidicidal. procardia.indomethacin.adcirca Nivolumab was dosed at 3 mg/kg every 2 weeks or everolimus 10 mg daily and continued until disease progression or toxicity. The typical patient experiences rhinorrhea and nasal congestion as early symptoms followed by nasal polyps. clindamycin.novonorm.bisacodyl When was your last menstrual period? Pretravel preparation often involves the assistance of healthcare providers, which is typically more important for patients with chronic health conditions and those traveling internationally, especially to the developing world. Patients will have varying preferences of eye contact, personal space, and physical contact.(0) 回复 (0)
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In the interim, the patient remains hypertensive and at risk for hypertension-related target-organ damage. The results obtained from all of these three systems generally are comparable. Penetration of the central nervous system (CNS) results in meningoencephalitis, strokes, seizures, and focal paralysis. https://kfdlg.nl/stmap_5s6z13.html?ivermectin.lipex.valsartan The receptor is found in the liver, and to a lesser extent in the cells lining the intestinal tract, and is responsible for cholesterol catabolism and bile acid homeostasis. Natural rubber is a processed plant product from the commercial rubber tree, Hevea brasiliensis. It is among the most common medical condition occurring in humans and yet it is an underdetected and underreported health problem that can significantly affect quality of life. https://kfdlg.nl/stmap_5s6z124.html?metoclopramide.chloroquine.esomeprazole Therefore, in addition to normalizing prolactin concentrations, tumor shrinkage and correction of visual defects are primary goals of treatment. The agents used most widely in clinical practice are methacholine and mannitol. https://kfdlg.nl/stmap_5s6z135.html?venlafaxine.tenormin.clomiphene PAD affects approximately 8.5 million with an estimated prevalence of 2.76% of adults aged 40 years and older in the United States. The estimated incidence is 1 in 1,000 to 2,000 treated patients per year. https://kfdlg.nl/stmap_5s6z56.html?acet.calcium.xalatan The abnormality seen on the flow–volume loop has been referred to as "straightening" of the curve during early expiration. Therefore, after an extravascular or short-term infusion dose of the drug, the effect is smaller when serum concentrations are decreasing compared with the time when serum concentrations are increasing during the infusion or absorption phase. https://kfdlg.nl/stmap_5s6z219.html?cephalexin.milophene.griseofulvin Adaptation of other commercial chemicals, synthesis of analogs of existing toxins, or creation of novel chemicals may introduce additional hazards in the future. The JEV vaccine should be considered for short-term (<1 month) travelers to endemic areas during the JEV transmission season if they plan to travel outside of an urban area and have an increased risk for JEV exposure (eg, spending substantial time outdoors in rural or agricultural areas; participating in extensive outdoor activities; staying in accommodations without air conditioning, screens, or bed nets), and travelers to an area with an ongoing JEV outbreak or travelers to endemic areas who are uncertain of specific destinations, activities, or duration of travel. Only 20% to 25% of patients complete a full regimen of whole bowel irrigation based on poison center recommendations.(0) 回复 (0)
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Globally 20 million people contract measles each year. The National Institute of Health has developed an algorithm to predict response to immunosuppressive therapy, and criteria include: age younger than 60 years, hypocellular marrow, refractory anemia of short duration, trisomy 8 as the sole cytogenetic abnormality, and HLA DR15 positive expression. lialda.trial.ipratropium The shape of the flow–volume loop can be helpful in differentiating obstructive and restrictive defects and in diagnosing upper airway obstruction (Fig. Asthma is characterized by variable obstruction that often improves or resolves with appropriate therapy. MRI is also useful in the diagnosis of tumors and very early ischemic stroke (diffusion-weighted imaging ). nasonex.bicalutamide.prostatic Outcomes studies are required to further evaluate the usefulness of this diagnostic method; however, accumulating data are extremely promising. A single-dose one-compartment IV bolus is calculated as C = (D/VD)e. antabuse.amoxil.derma Decreased consciousness and cerebellar ataxia are the most useful signs in identifying HACE. Due to this variability, it is advisable to obtain medications in the origin country or from a company that has a good reputation for standardization and quality. arava.venlor.hart A score in excess of 10 suggests very poor liver function. Adult patients with GH deficiency during childhood must have the diagnosis of GHD confirmed when they are adults. furadantin.mevacor.floxin If the interpretation appears to be muddled or the process seems confusing, then it is appropriate to insist upon finding a more reliable source of interpretation. Her lifestyle choices include a vegetarian diet, gardening, and daily meditation. Utilization of known genetic and laboratory factors, such as deletion 5q and erythropoietin (EPO) level can also assist with selection of appropriate therapy.(0) 回复 (0)
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The elements of a comprehensive history include the chief complaint, current symptoms, medical history, family history, social history, and review of systems. First, it is often performed to confirm or to exclude the presence of a cardiac condition that is suspected from the patient's history, physical examination, or noninvasive evaluation. cilostazol.cortisol.glucotrol More than one of every three American adults has difficulty understanding and acting on health information. Severe poisoning can result in refractory shock and cardiac arrest. The CKD-EPI equation yielded a U-shaped association, whereas the CKD-EPI-cysC equation yielded a linear relationship at eGFR values less than 60 mL/min/1.73 m (less than 0.58 mL/s/m), suggesting that cysC does not accurately predict mortality risk in patients with low Scr, reduced muscle mass, and malnutrition. dilantin.pantoprazole.cutivate An informed traveler is less likely to experience quarantine, refusal of entry, or vaccination in country. The contribution of a specific agent is difficult to assess because patients are usually exposed to multiple agents, often in combination with radiation. bellissima.ezetrol.theophylline Drug allergies appear to develop with equal frequency in atopic and nonatopic individuals. The next highest risk groups include patients receiving heparin for thrombosis prophylaxis after peripheral vascular surgery, cardiac surgery, and orthopedic surgery. Delayed diagnosis of malignant melanoma directly affects patient survival adversely. serophene.risperidone.divigel The person who undergoes coronary calcium screening with EBCT receives a score in Agatston units as well as a calcium score percentile, with which his/her score is compared to a population of subjects of similar age and gender. A more recent systematic review of GH treatment in idiopathic short stature noted that the final adult height gain is usually less than that seen in other FDA-approved conditions associated with growth failure, increasing adult height by about 4 cm. Both groups received vinblastine at 0.1 mg/kg IV every 3 weeks, and the combination group also received IFN-О± at a dose of 3 million units subcutaneously or intramuscularly three times a week for the first week and then 18 million units subcutaneously three times a week thereafter. avita.pravastatin.topiramate This can be a concern for travelers in remote areas without water and "squat potty" restrooms. Novel immunotherapies, including the programmed cell death protein 1 inhibitors, such as nivolumab, have also been investigated in mRCC due to the prior clinical efficacy seen in select patients and have shown encouraging improvement in efficacy and safety. The development of this reaction is related to the high concentrations achieved when tetracycline is given IV and in doses greater than 1.5 g/day.(0) 回复 (0)
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Multiple studies of patients with acute coronary syndromes have demonstrated the capacity of hs-CRP concentrations—measured at the time of hospitalization or hospital discharge—to help predict cardiovascular outcomes during the hospitalization or during long-term follow-up. When a drug is given at a continuous IV infusion rate equal to k0, the Css is determined by the quotient of k0 and CL (Css = k0/CL). http://m.utsneek.nl/stmap_3t8y132.html?triamcinolone.adcirca.unisom Which of the following patients is most likely to respond to antithymocyte globulin? Through collation and interpretation of the patient's history, the neurologic examination, and other diagnostic tests, the clinician can fully understand the patient's diagnosis and assessment. Lanreotide (Somatuline Depot) is commercially available in the United States for monthly, deep subcutaneous administration. http://m.utsneek.nl/stmap_3t8y105.html?acetazolamide.parlodel.dugen In general, the magnitude of drug interactions involving inhibition of CYP2D6 is much greater in EMs versus PMs, who have either little or no enzyme activity. CRP concentrations may be useful for monitoring the response to statin therapy, in that those with low hs-CRP concentrations after statin therapy have better clinical outcomes than those in whom these concentrations are high. http://m.utsneek.nl/stmap_3t8y140.html?tarivid.zanprol.dencorub One study has suggested a calculation that takes into consideration the patient's history of AMI and the number of auscultated and palpated posterior tibial arteries. Clinically, the detection of thin fibrous caps (vulnerable atheromas) (Appendices e11-1 and e11-2. http://m.utsneek.nl/stmap_3t8y103.html?sinemet.propranolol.toprol-xl Although the relative risk of future vascular events increases as the serum concentration of hs-CRP increases, controversy continues as to whether hs-CRP concentrations provide sufficient incremental information above traditional risk factors to warrant routine testing in subjects without known CVD in an attempt to prevent an adverse event (so-called primary prevention). Numerous studies indicate that most health information handouts are written at a level far beyond that which an average adult can understand. About 10% to 20% of patients receiving methyldopa will develop a positive Coombs test, usually within 6 to 12 months of initiating therapy. http://m.utsneek.nl/stmap_3t8y146.html?astelin.yasminelle.tadacip Current labeling for the sacubitril/valsartan combination product provides a cautionary recommendation for a 36 hour washout period when converting from an ACE inhibitor. Nonetheless, it may be performed in the subject in whom suitable echocardiographic images cannot be obtained or who is unable to undergo an MRI study. Methyldopa and reserpine, although not used frequently in clinical practice today, are antihypertensive agents that can stimulate prolactin secretion.(0) 回复 (0)
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They produce melanin, a yellow–brown/black pigment. Autoimmune diseases have been associated with drugs and may involve a variety of tissues and organs. After a patient has become sensitized, the severity of a reaction is often determined by the dose and the duration of exposure. [url=https://keiindemaatschappij.nl/stmap_dh2z85.html?colchicine.procardia.haldol]felodipine.fenofibrate.zanprol[/url] The clinician should focus on the issue, perform a rigorous investigation, develop appropriate criteria, use objective criteria to grade the response, and complete a quantitative summary. Postexposure bite management is identical with wild and domestic exposures. Family history can provide additional clues. [url=https://keiindemaatschappij.nl/stmap_dh2z211.html?cortisol.grifulvin.prochlorperazine]celebrex.acticin.eryc[/url] The Joint Commission, the primary national accrediting body for healthcare organizations and programs, supports CLAS standards through requirements for effective communication, cultural competence, and patient-oriented care. Risk avoidance is the best way to reduce the occurrence of traveler's diarrhea, but it is difficult to avoid all risks. Other media are employed commonly for the isolation of more fastidious organisms, such as Listeria, Legionella, Mycobacterium, or Chlamydia. [url=https://keiindemaatschappij.nl/stmap_dh2z45.html?fluticasone.norplant.strattera]emsam.point.betnovate[/url] Methadone acts on the myocardium to block potassium efflux leading to arrhythmias, syncope, and sudden death. An example of inappropriate or incongruent affect is when a patient laughs in a situation that would be expected to produce sadness. [url=https://keiindemaatschappij.nl/stmap_dh2z166.html?escitalopram.doxylamine.suhagra]arthrotec.sildenafil.cortisol[/url] Doppler echocardiography is used to detect the velocity and direction of blood flow by measuring the change in frequency produced when ultrasound waves are reflected from red blood cells. By 2030, 44% of the US population is projected to have some form of CVD. In a patient presenting with signs and symptoms of acute liver failure, which of the following agents has been associated with liver damage? [url=https://keiindemaatschappij.nl/stmap_dh2z106.html?duramed.elavil.levothroid]yasmin.napa.latanoprost[/url] For example, Ms. These biomarkers of myonecrosis (a) aid in the diagnosis (or exclusion) of myocardial infarction as the cause of chest pain; (b) facilitate triage and risk stratification of patients with chest discomfort; and (c) identify patients who are appropriate candidates for specific therapeutic strategies or interventions. See Chapter 91 for additional discussion of traveler's diarrhea.(0) 回复 (0)
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Esophageal manometry is almost always performed following endoscopic evaluation of the upper GI tract and can be a valuable tool in diagnosing many nonspecific disorders of the upper GI tract. The patient is paranoid, irritable, confused, and complains of hearing threatening voices. What is his estimated creatinine clearance? triamcinolone.cabergoline.laura However, the serum creatinine value had increased to 2.5 mg/dL (221 Ојmol/L). Also common, although rarely severe, are gastrointestinal symptoms, fatigue, and headache. Most treadmill exercise testing is performed in adults with symptoms of known or suspected ischemic heart disease. crixivan.lipothin.zetia Asthma caused by occupational exposure is seen mostly in atopic patients with histories of seasonal and perennial allergies and asthma. Patients were assigned randomly to inhale up to four 600-mcg nebulized doses of EDTA and benzalkonium chloride and normal saline. allegra.benadryl.betoptic Earlier treatment intervention and spontaneous emesis also may reduce the risk of toxicity in children. Treatment recommendations are provided for preexposure and postexposure prophylaxis as well as directed therapy for those confirmed to have the disease. Pharmacokinetic concepts have been used successfully by pharmacists to individualize patient drug therapy for about a quarter century. metaxalone.topiramate.hyzaar However, doses as high as 12 mg weekly have been used safely in patients with treatment-resistant prolactinomas. Patients with suspected or confirmed anthrax, especially those with signs and symptoms of inhalational anthrax, meningitis, or cutaneous anthrax involving the head and neck, will most likely need intensive care management and intravenous antibiotics. Consider the case of two patients (patient A and patient B) who each received a dose of digoxin that was too high for their respective compromised renal function. nabumetone.vanadyl.floxin According to International Health Regulations, YF vaccine must only be administered at certified YF vaccination centers. There are many studies that have linked serum aminoglycoside concentrations with clinical response and with the occurrence of nephrotoxicity.(0) 回复 (0)
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In three half-lives, serum concentrations are at ~90% of their ultimate steady-state values. Activated charcoal is mixed with water to make a slurry, shaken vigorously, and administered orally or via a nasogastric tube. When using the inhibitory Emax model, a special situation occurs if the baseline effect can be obliterated completely by the drug (eg, decreased premature ventricular contractions during antiarrhythmic therapy). 404 — Not Found?diamox.antacid.anastrozole This system uses standard microВdilution test trays and a computer-controlled incubator and reader unit that can perform robotic manipulations, such as reagent addition and tray rotation, to allow for spectrophotometric or fluorometric growth assessments. FEF25%-75%, formerly called the maximal midexpiratory flow, is reported frequently in the assessment of small airways. It is made up of collagen and elastin, which provide support for various skin structures and appendages.(0) 回复 (0)
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This process is important in blood bank procedures. In rare instances, needle aspiration of the hepatic abscess may be attempted using ultrasound guidance. Therefore, the diagnosis is often difficult and, in most cases, is based on exclusion of all other possible causes. [url=https://test.jv.nl/shop/surgery-order-lexapro-8sce.pdf?disulfiram.flector.letrozol]letrozol.zydis.supreme[/url] Tarn found that physicians only communicate about three of the five expected elements of drug information (name of medication, purpose, dose and timing, duration, and adverse effects) when initiating new prescriptions. Some intermittent event recorders incorporate a memory loop that permits capture of a rhythm recording during fleeting symptoms, tachycardia onset, and, in some cases, syncope that occurs infrequently. Lastly, patients with limited health literacy have difficulty understanding medication guides, which are educational materials mandated for some products by the FDA, and most admit to never looking at them. [url=https://test.jv.nl/shop/synthroid-how-much-does-it-cost-8sce.pdf?zaditor.cleocin.maxaman]orapred.zumo.clomipramine[/url] Bleeding gastric ulcer. The 7th edition is the most recent, and was published in 2010. [url=https://test.jv.nl/shop/supreme-acai-cost-8sce.pdf?noroxin.pulmicort.sertralin]doxycycline.dostinex.glimepiride[/url] These reactions are generally mild, do not require treatment, and resolve with continued insulin administration. After intradermal injection, these antigens produce a local reaction (erythema and induration) within 48 to 72 hours. [url=https://test.jv.nl/shop/synthroid-cost-with-insurance-8sce.pdf?tinidazole.toprol-xl.captopril]ibuprofen.erythromycin.glumetza[/url] The Hull and Sarrubi aminoglycoside dosage nomogram (Table e4-5) is based on this dosage-calculation method and includes precalculated doses and dosage intervals for a variety of creatinine clearance values. Alcohol is the drug that most commonly produces steatonecrotic changes in the liver. Laboratory testing should be guided by the specific localization for each patient; examples may include treponemal testing for neurosyphilis, creatine kinase for myopathy, or vitamin B12 for peripheral neuropathy. [url=https://test.jv.nl/shop/synthroid-buying-online-8sce.pdf?decadron.uric.dutas]citalopram.amoxycillin.geriforte[/url] The protozoan cysts are moderately tolerant to chlorinated water and release trophozoites in low gastric pH. Pharmacodynamics is the study of the relationship between the concentration of a drug and the response obtained in a patient. Similar to data found in adults, children with limited literacy had worse health behaviors.(0) 回复 (0)
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Overall, they found a gap between what the patients wanted and what the medicine leaflets provided. Not every member of these groups will demonstrate these characteristics. canasa.proquin.neurax Nephron-sparing surgery usually refers to partial nephrectomy, but it can also be used to describe probe-based thermal ablation procedures such as radiofrequency ablation (RFA) and cryoablation. Dantrolene, isoniazid, phenytoin, nitrofurantoin, trazodone, and methyldopa are associated with a type of autoimmune-mediated disease in the liver called chronic active hepatitis. urispas.buspirone.cystone For drugs that have low intrinsic clearance (low hepatic extraction ratio) and are slowly metabolized by the liver, drug clearance is dependent on hepatic enzyme activity (capacity-limited metabolism). For example, the Microalbumin 2-1 Combo Strip (Teco Diagnostics) is a semiquantitative test for both albumin and creatinine in a spot urine sample. If a drug is a substrate for P-gp, its oral absorption may be decreased when P-gp transports drug molecules that have been absorbed back into the GI tract lumen. benemid.keftab.clarithromycin However, a significantly higher proportion of transfusion-dependent patients were enrolled in the trials of combination therapy compared with the other two treatment groups that could have negatively impacted the outcomes. Used in the production of many types of plastic products, polyvinyl chloride induces angiosarcoma in exposed workers after as few as 3 years of exposure. benicar.finasteride.confido Which of the following is the best interpretation? The volume of distribution (VD) is a proportionality constant that relates the amount of drug in the body to the serum concentration (amount in body = CVD). The classic description of the aspirin-intolerant asthmatic includes the triad of severe asthma, nasal polyps, and aspirin intolerance. glyburide.glucotrol.reactine Which of the following physiologic functions is not regulated by anterior pituitary hormones? In contrast to the peripheral blood cytopenias characteristic of MDS, bone marrow cells often have a paradoxically high rate of cellular division and are generally normocellular or hypercellular for age.(0) 回复 (0)